Westin Market Street, a 35-story, 681-room hotel located at 50 Third St. in San Francisco's Yerba Buena district, sold to Bethesda, MD-based multi-operator real estate investment trust LaSalle Hotel Properties (NYSE: LHO) for $350 million, or approximately $514,000 per key, in the largest hotel transaction in San Francisco since Chicago-based Strategic Hotels & Resorts' acquisition of the 1,195-room Westin St. Francis in 2006 for $440 million.