Breakthrough Properties, a joint venture between global real estate owner, developer and investor Tishman Speyer and biotechnology investment firm Bellco Capital, has commenced construction on the redevelopment of the former Canal Park office building into a four-story lab and office building in East Cambridge, Massachusetts. The property at 1 Canal Park was acquired by Breakthrough in 2021 and is being retrofitted to accommodate more than 105,000 square feet of research and development space.